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Pashtoon Kasi Shared ASCO25 Results on ADG126 + Pembrolizumab in MSS Colorectal Cancer Without Liver Metastases
Jun 4, 2025, 23:12

Pashtoon Kasi Shared ASCO25 Results on ADG126 + Pembrolizumab in MSS Colorectal Cancer Without Liver Metastases

Pashtoon Kasi, Medical Director of GI Medical Oncology at City of Hope Orange County, shared on LinkedIn:

“ASCO 2025 Continuing with the immunotherapy promise for a new subset of patients with no active liver metastases (NLM), MSS colorectal cancer – watch this:
ADG126 (Masked CTLA-4 Inhibitor) + Pembrolizumab
ORR ~29%, Sustained reduction observed.
FRUQ + Immunotherapy arm.”

Pashtoon Kasi

Title: Safety and efficacy of ADG126 (an anti-CTLA-4 masking antibody) in combination with pembrolizumab: Updated results of phase 1b/2 study in advanced MSS CRC

Journal: ASCO, JCO

Authors: Daneng Li, Sun Young Kim, Manish Patel, Hee Kyung Kim, Sunil Sharma, Sang Joon Shin, Jeeyun Lee, Sae-Won Han, Luke Chung, Songmao Zheng, Yan Li, Ping Xiao, Kristine She, Dana HuLowe, Jiangchun Xu, Stanley Frankel, Michael Chisamore, Peter Luo, Jiping Zha, Marwan Fakih

Read the full abstract.

Pashtoon Kasi

More posts featuring Pashtoon Kasi on OncoDaily.