December, 2024
December 2024
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Myeloma Paper of the Day, December 4th, suggested by Robert Orlowski
Dec 4, 2024, 14:15

Myeloma Paper of the Day, December 4th, suggested by Robert Orlowski

Robert Orlowski shared a post on X:

“Myeloma Paper of the Day: A systematic review and meta-analysis of quadruplet regimens for patients with newly diagnosed myeloma finds quads increase ORR, PFS, MRD negativity (@ 10-5 and 10-6) and OS with a slight increase in rates of grade 3-4 infections.”

Quadruplet regimens for patients with newly diagnosed multiple myeloma: a systematic review and meta-analysis

Authors: Mohammad S. Ebraheem, Rajshekhar Chakraborty, Bram Rochwerg, Alissa Visram, Ghulam Rehman Mohyuddin, Christopher P. Venner, Irwindeep Sandhu, Arleigh McCurdy, Thierry Facon, Maria-Victoria Mateos, Hira Mian

Myeloma Paper of the Day, December 4th, suggested by Robert Orlowski

More posts featuring Robert Orlowski.

Robert Orlowski, M.D., Ph.D., holds multiple positions at The University of Texas MD Anderson Cancer Center, including Chairman, Ad Interim Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics within the Division of Cancer Medicine. Additionally, he chairs the SWOG Barlogie/Salmon Myeloma Committee, which is part of the National Clinical Trials Network, dedicated to advancing new therapies and understanding the biology of myeloma.

Dr. Orlowski’s expertise lies in both clinical practice and scientific research, with a particular focus on translating laboratory discoveries into effective treatments for patients. He investigates drug resistance mechanisms in myeloma and seeks to identify predictive biomarkers for treatment response. Notably, his past contributions include leadership roles in developing proteasome inhibitors like bortezomib and carfilzomib, as well as monoclonal antibodies such as daratumumab and elotuzumab.