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Mario Balsa: ASCO 2025 Guideline Updates on Stage IV NSCLC with Driver Alterations 
Jul 30, 2025, 13:12

Mario Balsa: ASCO 2025 Guideline Updates on Stage IV NSCLC with Driver Alterations 

Mario Balsa, Medical Oncology resident at Institut Català d’Oncologia (ICO), shared on X about a recent paper by Joshua E. Reuss  et al. published in JCO:

ASCO 2025 guideline updates on stage IV NSCLC with driver alterations

  • EGFR: Osimertinib remains top
  • ALK: Alectinib or Lorlatinib. ¿Brigatinib? Twirl and exit
  • KRAS G12C: Sotorasib/Adagrasib post-CT

A living document for a fast-evolving field. Lung cancer doesn’t stand still, and neither should we.”

Title: Therapy for Stage IV Non–Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2025.1

Authors: Joshua E. Reuss, Sara Kuruvilla, Nofisat Ismaila, Ibrahim Hanna Azar, Jill Feldman, Naoki Furuya, Paul Wheatley-Price, Logan Roof, Ana I. Velazquez, Yubao Wang, Natasha B. Leighl.

Read the full article.

Mario Balsa

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