Manoj Reddy: The Role of AI in Radiation Oncology

Manoj Reddy, Founder and President of IOWG, shared a post on LinkedIn:

“The Role of AI in Radiation Oncology: Balancing High Technology with Patient-Centered Care.

Radiation oncology is undergoing a transformative era with artificial intelligence (AI) at its core.

From automating contouring to adaptive radiotherapy, AI is reshaping cancer care delivery.

This post highlights key advancements, emerging trends, and their implications for the future of cancer care.

Advancements in AI-Driven Radiation Oncology

Automated Contouring:

Manual contouring of organs-at-risk (OARs) and target volumes is one of the most time-consuming steps in radiation therapy planning. AI-based tools are addressing this challenge, improving efficiency and accuracy while allowing clinicians to focus on patient care.

• A recent study comparing AI tools like MIM Software MIM Protégé AI+, Radformation Radformation-Auto Contour, and Siemens Siemens-Direct ORGANS demonstrated significant time savings and high accuracy compared to manual methods: Goddard et al, Radiation Oncology, 2024.
• Another study reviewed eight AI auto-contouring programs, including MVision AI, Limbus AI, and There Panacea highlighting their potential to reduce variability and improve efficiency. Meyer et al, Radiation Oncology 2024.

Adaptive Radiotherapy:

AI enables real-time treatment adjustments based on tumor or anatomy changes, providing highly personalized care:

• Varian (Siemens Healthineers): The Ethos™ system enhances efficiency by significantly reducing treatment planning times, allowing oncologists more time to engage with patients (Mirel, AMA-Assoc, 2024).
• Elekta: Systems like Unity and Evo systems use AI to enhance imaging and automate workflows for adaptive radiotherapy.
• Accuracy: Synchrony® tracks and adjusts for real-time tumor motion, while PreciseART® automates offline adaptations.

Future Trends in AI for Radiation Oncology

AI Enhancing Workflow Integration:

Emerging tools like LLMSeg, a multimodal AI model integrating clinical text with target volume delineation, are revolutionizing radiation oncology workflows. (Oh et al., arXiv, 2023).

End-to-End AI Automation:

Transformer-based models like Swin UNETR++ are paving the way for fully automated radiation therapy workflows (Wang et al., arXiv, 2023)

Bridging Gaps in Access:

AI is democratizing access to radiation oncology, particularly in underserved regions:

• Hundreds of thousands of cancer patients in low- and middle-income countries lack access to radiation therapy (Christ et al., Adv Radiat Oncology, 2023).
• The Radiation Planning Assistant (RPA), developed by MD Anderson Cancer Center, automates treatment planning, making advanced care accessible without requiring specialized expertise (Bloom et al., MD Anderson, 2024).

AI’s Role in Patient-Centered Care

While AI enhances efficiency, it cannot replace the empathy and clinical judgment of radiation oncologists.

A study from the European Society for Medical Oncology highlights how AI-driven workflows reduce burnout, enabling oncologists to focus on building trust with their patients (Heudel et al., ESMO Open, 2024).

Reflections

As AI continues to redefine the landscape of radiation oncology, the opportunities for collaboration between clinicians, researchers, and technology developers are immense.

The potential to enhance care quality, reduce disparities, and optimize workflows is transformative.

I’m always eager to engage with peers and innovators driving this evolution.

How do you see AI shaping the future of oncology care?

What challenges and opportunities do you anticipate as we integrate these advancements into clinical practice?

Let’s discuss in the comments.

Views expressed are my own and do not reflect the views of the Department of Veteran Affairs or the United States Government.”

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