
Diego A. Díaz García/X
Jun 30, 2025, 06:57
Diego A. Díaz García Reflects on Nature Study Highlighting Challenges in Targeting Tumor-Infiltrating Tregs
Diego A. Díaz García, Medical Oncologist / CEO / Founder at CánCare – Advanced Specialty in Oncology, shared on X about a recent paper shared by Charlotte J. Imianowski et al. published in Nature:
“Tumor-infiltrating Tregs: powerful allies of cancer.
Targeting them is promising, but tricky.
They share biology with CD4+ T cells, and systemic depletion risks immune toxicity.We need smarter strategies to selectively disrupt them in the TME.”
Title: Regulatory T cells in the tumour microenvironment
Authors: Charlotte J. Imianowski, Qiang Chen, Creg J. Workman and Dario A. A. Vignali
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