News Feed Opinion Blog Career Insight Dialogues Celebrities Oncolibrary
Positive Societies Drugs Stories History Cancer Center Near Me Cancer Types Immune Oncology Oncologist Near Me
June, 2025
June 2025
M T W T F S S
 1
2345678
9101112131415
16171819202122
23242526272829
30  
Christopher Flowers shared an article on Large B cell lymphoma microenvironment archetype profiles
mdanderson.org
Jun 21, 2025, 19:31

Christopher Flowers shared an article on Large B cell lymphoma microenvironment archetype profiles

Christopher Flowers, Division Head of Cancer Medicine at MD Anderson Cancer Center, shared a post on LinkedIn:

“Exciting news from the plenary session of ICML where David Russler-Germain from Wash U presented on “Large B-cell Lymphoma Microenvironment Archetype Profiles (LymphoMAPs) identify subgroups of patients with large B-cell lymphoma (LBCL) with greater benefit from CD19 CAR T-cell therapy”. Steve Ansell from Mayo Clinic provided an outstanding commentary on the work.
The LymphoMAPs framework defined three reproducible tumor microenvironment (TME) archetypes (FMAC, LN, TEX) with distinct cellular ecosystems, novel prognostic insights, and potential targets for personalized treatment strategies. LymphoMAPs are orthogonal to malignant clone genetics and critically shape immune dynamics and therapeutic outcomes. This work was led by Dr. Michael Green and his lab at MD Anderson. Complete details of this work are now published in Cancer Cell.”

Title: Large B cell lymphoma microenvironment archetype profiles

Authors: Xubin Li, Kartik Singhal, Qing Deng, Dai Chihara, David Russler-Germain, R. Andrew Harkins, Jared Henderson, Kotaro Arita, Atish Kizhakeyil, Ryan Sun, Priya Lakra, Usama Hussein, Jennifer A. Foltz, Ashley Wilson, Evelyn Schmidt, Imran Nizamuddin, Tommy Dinh, Akhil Kesaraju, Mark P. Hamilton, Carl Allen, Maher K. Gandhi, Joshua Tobin, Aixiang Jiang, Laura Hilton, David W. Scott, Francisco Vega, Christopher R. Flowers, Jason R. Westin, Obi L. Griffith, Todd A. Fehniger, Malachi Griffith, Michael R. Green

Read the Full Article.

Christopher Flowers

Aixiang Jiang Akhil Kesaraju Ashley Wilson Atish Kizhakeyil cancer Carl Allen Christopher Flowers Christopher R. Flowers Dai Chihara David Russler-Germain David W. Scott Evelyn Schmidt Francisco Vega Imran Nizamuddin Jared Henderson Jason R. Westin Jennifer A. Foltz Joshua Tobin Kartik Singhal Kotaro Arita Laura Hilton lymphoma LymphoMAPs Maher K. Gandhi Malachi Griffith Mark P. Hamilton Michael R. Green Obi L. Griffith OncoDaily Oncology Priya Lakra Qing Deng R. Andrew Harkins Ryan Sun Todd A. Fehniger Tommy Dinh Usama Hussein Xubin Li
Special Coverage
Blog
Jun 25, 2025, 09:08
Laura Bukavina: How Do We Predict Patients with True CR Using Urine Biomarkers?
Science
Jun 25, 2025, 09:08
Myeloma Paper of the Day, June 25th, suggested by Robert Orlowski
Blog
Jun 25, 2025, 09:07
Mikkael Sekeres: Can BPAs, PFAS, or Phthalates in Everyday Household Items Can Cause Cancer?
Insight
Jun 25, 2025, 09:00
Stephen V Liu on Phase 2 Study of Irinotecan plus Anlotinib for Platinum-Resistant SCLC
Insight
Jun 25, 2025, 08:59
David Tougeron Shared Study on Prognostic Tool for Third-Line Chemotherapy in Unresectable Pancreatic Cancer
Insight
Jun 25, 2025, 08:58
Zainul Aabideen Shared Details Upcoming "Pediatric Bone Marrow Transplant Course 2025"
Blog
Jun 25, 2025, 08:57
Digestive Cancers Europe Prepares for 10th DiCE Masterclass in Barcelona
Blog
Jun 25, 2025, 08:48
50 States in 50 Days with Ryan Trahan and Kia for Raising Awareness and Funds for Kids - St. Jude Children's Research Hospital
Blog
Jun 25, 2025, 08:46
Wee Joo Chng: We Concluded Another International Myeloma Study Group Summit - The Progress Has Been Tremendous
Dialogues
Jun 25, 2025, 08:45
Women Leaders in Oncology: Tara Frenkl on Hope, Elinzanetant, and HER2+ Lung Cancer Advances
Blog
Jun 25, 2025, 08:44
Luigi Formisano: Hot Topics at the 2025 GUiding INNOVATION Meeting
Blog
Jun 25, 2025, 08:43
Peter Pisters: I am Grateful to Our Nursing Community for Their Continued Commitment to Excellence for Our Patients