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Anirban Maitra: In Vivo Screening Reveals Cell-Intrinsic Mediators of Solid Tumor Resistance to CAR T Cell-Therapy

Anirban Maitra/LinkedIn

Aug 1, 2025, 19:58

Anirban Maitra: In Vivo Screening Reveals Cell-Intrinsic Mediators of Solid Tumor Resistance to CAR T Cell-Therapy

Anirban Maitra, Professor at MD Anderson Cancer Center, shared a post on X:

“New preprint from Hemann lab

In vivo screening reveals cell-intrinsic mediators of solid tumor resistance to CAR T cell-therapy. CRISPR screens in Pancreatic Cancer model identifies Nrf2 hyperactivity as a sensitizer to CAR-T cell therapy.”

Title: In vivo screening reveals cell-intrinsic mediators of solid tumor resistance to CAR T cell-therapy

Authors: Julia Fröse, Charles A. Whittaker, Paul Leclerc, Evelyn Chen, Sean Doherty, Adam Langenbucher, Riley D. Hellinger, Daniel Goulet, Tuomas Tammela, Michael T. Hemann

Read the Full Article.

Anirban Maitra

Adam Langenbucher Anirban Maitra cancer CAR T-cell therapy Charles A. Whittaker Daniel Goulet Evelyn Chen Julia Fröse Michael T. Hemann OncoDaily Oncology Paul Leclerc Riley D. Hellinger Sean Doherty Tuomas Tammela

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