Insight

Jul 1, 2024, 01:36

Challenges in delivering radiotherapy to lymph nodes in rectal cancer

Nina Niu Sanford shared a post by Ane Appelt, Associate Professor at the University of Leeds, on X, adding: .

“Nice paper. I find the treatment of lymph nodes challenging in rectal cancer.

In OCUM study, MRI accuracy for predicting LN (lymph nodes) involvement at diagnosis only 56% (basically a coin flip).

And then post neoadjuvant treatment even trickier (and some completely disappear).”

Quoting Ane Appelt’s post:

“How much margin do we need on individual lymph nodes when delivering rectal cancer radiotherapy?

Dennis Tideman Arp ran a prospective MRI study (physicist as PI (Principal Investigator)!) and estimated node position variation over the course of RT (Radiation therapy).”

Proceed to the article.
Source: Nina Niu Sanford/X and Ane Appelt/X

Dr. Nina Niu Sanford is an Assistant Professor and Chief of Gastrointestinal Radiation Oncology at Harvard/Brigham and Women’s Hospital/Massachusetts General Hospital. She specializes in treating gastrointestinal cancers and actively participates in clinical trials combining high-dose radiation therapy with immunotherapy. Additionally, she researches healthcare access disparities and conducts pan-cancer outcomes research using large databases.

Ane Appelt Brigham and Women's Hospital cancer Dennis Tideman Arp lymph nodes MRI accuracy Nina Niu Sanford OCUM OncoDaily Oncology radiation therapy rectal cancer RT University of Leeds

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