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Yan Leyfman: Pioneering work that is enhancing NK CAR efficacy
Katy Rezvani/mdanderson.org
Jun 23, 2024, 05:10

Yan Leyfman: Pioneering work that is enhancing NK CAR efficacy

Yan Leyfman, Internal Medicine and Clinical Researcher at Icahn School of Medicine at Mount Sinai, shared a post on LinkedIn:

“Pioneering work that is enhancing NK CAR efficacy.

Authors showed that the incorporation of CD28 costimulation, which is normally absent in NK cells, in the CAR construct improves efficacy of CAR NK cells via the LCK/CD3ζ/ZAP70 pathway.

Congratulations to Katy Rezvani and team on the pioneering work.”

Yan Leyfman

Additional information.
Source: Yan Leyfman/LinkedIn

Alexander Biederstadt Ali Rezvan Ana Karen. Nunez Cortes Antrix Jain Bijender Kumar Bin Liu cancer CD28 Chenyu Zhang David Marin Elizabeth J. Shpall Emily Ensley Enli Liu Francia Reyes-Silva Francisco Vega Gary M. Deyter Hind Rafei Icahn School of Medicine Janos Roszik Joseph D. Khoury Katayoun Rezvani Katy Rezvani Ken Chen Kiran Kundu Kun Hee Kim LCK/CD3ζ/ZAP70 pathway Luciana Melo Garcia Luis Muniz-Feliciano Luisa M. Solis Soto Maria Gabriela Raso May Daher Mayra Shanley Mecit Kaplan Melisa J. Montalvo Mohsen Fathi Nadima Uprety Natalie W. Fowlkes Navin Varadarajan NK CAR NK cells OncoDaily Oncology Paul Lin Pei Lin Pinaki P. Banerjee Ping Li Rafet Basar Rejeena Shrestha Sophia L. Cha Sunil Acharya Vakul Mohanty Xianli Jiang Xin Ru Jiang Xingliang Guo Yan Leyfman Ye Li Yuchen Pan
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