![Abhishek D. Garg: Thrilled to share our lab’s latest research on multiomics and spatial mapping of immunotherapy responses in kidney cancer patients](https://oncodaily.com/pub/uploads/2023/11/download-92-e1716482504817-1280x960.jpg)
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May 23, 2024, 15:09
Abhishek D. Garg: Thrilled to share our lab’s latest research on multiomics and spatial mapping of immunotherapy responses in kidney cancer patients
Abhishek D. Garg,
“Thrilled to share our lab’s latest research on multiomics and spatial mapping of immunotherapy responses in kidney cancer patients in Nature Medicine.
- We found that heritable and spatial immunogenic traits co-predict the efficacy of immunotherapy in kidney cancer patients.
- An artificial intelligence or machine learning-derived gene signature, integrating germline HLA characteristics with a distinct spatial community of CD8+T cells and tumor-associated macrophages showing immunogenic interactions, predicts response to immunotherapy in patients with advanced kidney cancer.
- Our biomarker works in both controlled clinical trials as well as real-world patient cohort, which emphasizes its clinical readiness and utility potential.
- We also demonstrate how our biomarker can be used for discovery of new immunotherapy targets or for informing new combinatorial therapy designs!
Read the research here.
This brilliant work was made possible because of a series of collaborators and our lab mates, especially Benoit Beuselinck, Lisa Kinget and Stefan Naulaerts! .
Thanks also to Isaure Vanmeerbeek, Raquel Laureano, Jannes Govaerts, Jenny Sprooten, Francesca Finotello, Maarten Albersen, Diether Lambrechts, Francesca Maria Bosisio, Johan Kerkhofs and others!
Thanks also to all our funders, sponsors and supporters.”
Source: Abhishek D. Garg/LinkedIn
Abhishek D. Garg
Benoit Beuselinck
cancer
Cell Stress and Immunity (CSI)
clinical trials
Diether Lambrechts
Francesca Finotello
Francesca Maria Bosisio
Isaure Vanmeerbeek
Jannes Govaerts
Jenny Sprooten
Johan Kerkhofs
kidney cancer
KU Leuven
Lisa Kinget
Maarten Albersen
Nature Medicine
OncoDaily
Oncology
Raquel Laureano
Stefan Naulaerts
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ASCO Annual Meeting
May 30 - June 4, 2024
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Yvonne Award 2024
May 31, 2024
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OncoThon 2024, Online
Feb. 15, 2024
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Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023