![Robert Z. Orlowski: Nice review of tumor-intrinsic and -extrinsic resistance mechanisms to T-cell engagers](https://oncodaily.com/pub/uploads/2024/03/GJP9vQzWkAA1y_Q.jpeg)
Photo taken from: Robert Z. Orlowski/X
Mar 27, 2024, 00:40
Robert Z. Orlowski: Nice review of tumor-intrinsic and -extrinsic resistance mechanisms to T-cell engagers
Robert Z. Orlowski, Director of Myeloma Section at MD Anderson Cancer Center, posted on X/Twitter:
“Myeloma Paper of the Day: Nice review of tumor-intrinsic (loss of target antigen, MHC class I, preventing MHC class I:TCR co-stimulatory signaling) and -extrinsic resistance mechanisms (exhausted T cells & immunosuppressive TME) to T-cell engagers.”
Read the paper.
Source: Robert Z. Orlowski/X