Article summaries by Erman Akkus: BMI and cancer prognosis and billiary tract cancer

Erman Akkus, Medical Oncology Fellow at Ankara University, shared a post on X/Twitter:

1. ”BMI, weight change, and cancer prognosis: a meta-analysis of 73 cohort studies ESMO Open.

Obesity vs. normal weight

• worse OS: breast cancer, glioblastoma;
• better OS: GI, lung and renal cancers;

Underweight vs. normal weight

• worse OS: breast, GI, lung, head and neck cancers

Weight loss vs. nonweight change

• worse OS: GI cancers

Keeping normal body weight before and after diagnosis of the cancer may be the best.”

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Source: Erman Akkus/X

2. ”Biliary Tract Cancers: French National Clinical Practice Guideline.

• Localized disease: surgery and adjuvant capecitabine.
• No neoadjuvant treatment is validated to date.
• Advanced disease: Cisplatin-gemcitabine-durvalumab.
• Early biomarker testing.
• Second line: FOLFOX.”

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Source: Erman Akkus/X