Ilia Kurochkin: New Paths for Cancer Immunotherapy Through Direct Cell Reprogramming
Aug 30, 2025, 21:11

Ilia Kurochkin: New Paths for Cancer Immunotherapy Through Direct Cell Reprogramming

Ilia Kurochkin, Postdoctoral Researcher at Lund University, shared a post on LinkedIn:

“Out now.
Our paper is now online in Immunity

In our study, we chart new paths for cancer immunotherapy through direct cell reprogramming. We discovered two transcription factor combinations that convert skin and cancer cells into distinct dendritic cell (DC) subsets, each triggering unique anti-tumor responses and establishing long-lasting immune memory.

I’m especially proud of conducting the bioinformatics analyses that disentangled the gene regulatory networks controlling the identity of these reprogrammed cells — insights that pave the way for designing next-generation DC-based immunotherapies.

Thank you to Filipe Pereira, all of the co-authors, collaborators, and the funding agencies whose support made this work possible — especially the Cancer Research Institute (CRI). Another big thank you to my incredible co-first authors, Luís Oliveira, PhD, and Abigail A. — sharing this journey with you has been unforgettable.”