Raffaele Colombo/LinkedIn
Mar 27, 2025, 16:40
Raffaele Colombo: First ever dual payload ADC in the clinic
Raffaele Colombo, Associate Director of Medicinal Chemistry at Zymeworks, shared a post on X:
“First ever dual payload ADC in the clinic by Chengdu Kanghong Biotech! KH815, a dual-payload ADC targeting TROP2.
Payloads:
“Drug-T” and “Drug-E”
And one of the two payloads is definitely a topoisomerase I inhibitor.”
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