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JeeSuk Chang: A multi-center trial – great efforts from the KROG team
Nov 29, 2023, 17:28

JeeSuk Chang: A multi-center trial – great efforts from the KROG team

JeeSuk Chang,

“1. Check out our new paper exploring the potential clinical utility of deep learning auto-contouring for clinical target volume, organs at risk in breast cancer Radiation Therapy Quality Assurance within a multi-center trial. Great efforts from the KROG team and credit to the first author, Chloe Min Seo Choi. 31 centers participated.
For the article click here.

JeeSuk Chang: A multi-center trial - great efforts from the KROG team

JeeSuk Chang: A multi-center trial - great efforts from the KROG team

2. Over 800 pairwise comparisons showed significant improvement in inter-observer variation with auto-contour intervention. Participants’ contours aligned with auto-contour reference shapes in 2D and 3D, pinpointing common adjustments in local anatomical regions.

JeeSuk Chang: A multi-center trial - great efforts from the KROG team

JeeSuk Chang: A multi-center trial - great efforts from the KROG team

3. Cluster analysis based on CTV volumes classified contouring styles, potentially laying the groundwork for reducing inter-observer variations. For instance, certain centers (red) inclined to contour larger than average were identified.

JeeSuk Chang: A multi-center trial - great efforts from the KROG team

4. Along with education, audits, site credentialing, and peer reviews, using auto-contours for CTV and OARs can be a novel approach to minimize RT protocol deviations in multi-center trials.”

Source: JeeSuk Chang/Twitter