Anirban Maitra: Preclinical studies in lung cancer using a KRAS G12V directed PROTAC
Anirban Maitra, Professor of Pathology and Translational Molecular Pathology at UT MD Anderson Cancer Center, shared on X:
“New preprint from Cris Mayor-Ruiz on preclinical studies in lung cancer using a KRAS G12V directed PROTAC. Targeted KRAS(G12V) degradation elicits efficient and durable lung adenocarcinoma regression in vivo. Link to preprint.”
Targeted KRAS(G12V) degradation elicits efficient and durable lung adenocarcinoma regression in vivo
Authors: Alberto Martín, Inés M. García-Pérez, Sonia San José, Pep Rojo, Carlos Riego-Mejías, Cristina Teodosio, Bárbara MG. Barbosa, Carolina Sánchez-Zarzalejo, Ignasi Folch-I-Casanovas, Antonia Odena Caballol, Sònia Jarió, Rodrigo Entrialgo, Marie-Julie Nokin, Diana Loa, Elizabeth Guruceaga, Camille Stephan-Otto Attolini, Chiara Ambrogio, Alberto Villanueva, Silvestre Vicent, Antoni Riera, David Santamaría, Cristina Mayor-Ruiz
Dr. Anirban Maitra serves as Professor of Pathology and Translational Molecular Pathology at UT MD Anderson Cancer Center since August 2013, and directs the Sheikh Ahmed Pancreatic Cancer Research Center. He leads an NCI-funded laboratory dedicated to pancreatic cancer research, focusing on genetics and molecular pathology in human and mouse models. His research aims to advance early detection and interception strategies to enhance patient survival rates in pancreatic cancer.
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