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Carman Man-Chung Li: Hidden Mechanisms of BRCA1 Hereditary Breast Cancer

Carman Man-Chung Li/croucher.org.

Nov 18, 2024, 08:33

Carman Man-Chung Li: Hidden Mechanisms of BRCA1 Hereditary Breast Cancer

Carman Man-Chung Li, Postdoctoral Fellow at Harvard Medical School, shared a recent article on X:

“Our latest paper with Joan Brugge is now out at Orli Bahcall. We explore hidden mechanisms of BRCA1 hereditary breast cancer using new mouse models, revealing unexpected tumor-like chromatin changes in Brca1-heterozygous normal mammary cells.”

Title: Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer

Authors: Carman Man-Chung Li, Alyssa Cordes, Michael U. J. Oliphant, S. Aidan Quinn, Mayura Thomas, Laura M. Selfors, Francesca Silvestri, Nomeda Girnius, Gianmarco Rinaldi, Jason J. Zoeller, Hana Shapiro, Christina Tsiobikas, Kushali P. Gupta, Shailja Pathania, Aviv Regev, S. Cigall Kadoch, Senthil K. Muthuswamy and Joan S. Brugge

Carman Man-Chung Li

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Alyssa Cordes Breast Cancer cancer Carman Man-Chung Li Joan S. Brugge mammary cells Mayura Thomas Michael U. J. Oliphant OncoDaily Oncology Orli Bahcall S. Aidan Quinn S. Cigall Kadoch Senthil K. Muthuswamy tumor

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