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Single-cell RNA sequencing shows relevance for drug target selection

Emma Dann/LinkedIn

Nov 8, 2024, 19:29

Single-cell RNA sequencing shows relevance for drug target selection

A recent paper by Emma Dann, EMBO post-doctoral fellow in the Pritchard Lab at Stanford University, was mentioned by Marios Georgakis, Emmy Noether Research Group Leader and Clinician at LMU Munich, on X:

“Beyond genomics, single-cell RNA sequencing also shows relevance for drug target selection.

Targets with

high expression in disease-relevant cell types or
cell-type overexpression in disease patients,

are more likely to proceed in clinical development.”

“Estimating the impact of single-cell RNA sequencing of human tissues on drug target validation”

Authors: Emma Dann, Erin Teeple, Rasa Elmentaite, Kerstin Meyer, Giorgio Gaglia, Frank Nestle, Virginia Savova, Emanuele de Rinaldis, Sarah Teichmann.

Single-cell RNA sequencing shows relevance for drug target selection

More posts about single-cell RNA sequencing.

Emma Dann is a computational biologist with expertise in analyzing single-cell genomics data. She is currently an EMBO postdoctoral fellow at the Pritchard Lab at Stanford University and the Gladstone Institutes, as well as a visiting fellow in the Marson Lab at the Gladstone Institutes.

cancer Emanuele de Rinaldis Emma Dann Erin Teeple Frank Nestle Giorgio Gaglia Kerstin Meyer Marios Georgakis OncoDaily Oncology Rasa Elmentaite Sarah Teichmann single-cell RNA sequencing Virginia Savova

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