Myeloma Paper of the Day, October 4th, suggested by Robert Orlowski

Robert Orlowski shared on X:

“Myeloma Paper of the Day: In a cohort of 220 patients with newly diagnosed MM, attainment of MRD- offered favourable outcomes (P < 0.0001 for both PFS & OS) and most patients (70%) who lost MRD- status carried high-risk cytogenetic abnormalities.”

Source: Robert Orlowski/X

Dynamics of minimal residual disease and its clinical implications in multiple myeloma: A retrospective real-life analysis

Authors: Weiling Xu, Xinyue Liang, Shanshan Liu, Xingcheng Yi, Mengru Tian, Tingting Yue, Yingjie Zhang, Yurong Yan, Maozhuo Lan, Mengtuao Long, Nan Zhang, Jingxuan Wang, Xiaoxiao Sun, Rui Hu, Yufeng Zhu, Xintian Ma, Yue Cheng, Jiayi Xu, Yun Dai, Fengyan Jin.

Other posts featuring Robert Orlowski on OncoDaily.

Robert Orlowski, M.D., Ph.D., holds multiple positions at The University of Texas, MD Anderson Cancer Center including Chairman, Ad Interim Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics within the Division of Cancer Medicine. Additionally, he chairs the SWOG Barlogie/Salmon Myeloma Committee, which is part of the National Clinical Trials Network, dedicated to advancing new therapies and understanding the biology of myeloma.

Dr. Orlowski’s expertise lies in both clinical practice and scientific research, with a particular focus on translating laboratory discoveries into effective treatments for patients. He investigates drug resistance mechanisms in myeloma and seeks to identify predictive biomarkers for treatment response. Notably, his past contributions include leadership roles in developing proteasome inhibitors like bortezomib and carfilzomib, as well as monoclonal antibodies such as daratumumab and elotuzumab.