Insight

Vince Luca: The structure of LAG3 bound to MHC-II

Photo taken from Vince Luca/X

Sep 2, 2024, 12:56

Vince Luca: The structure of LAG3 bound to MHC-II

Vince Luca, Associate Professor at Moffitt Cancer Center, shared on X:

“I am excited to share our Nature Communications paper describing the structure of LAG3 bound to MHC-II. This project was carried out by Qianqian Ming et al. at Moffitt Research and provides new insights into the mechanism by which LAG3 suppresses T cell activation.”

Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab

Authors: Qianqian Ming, Daniel Antfolk, David A. Price, Anna Manturova, Elliot Medina, Srishti Singh, Charlotte Mason, Timothy H. Tran, Keiran S. M. Smalley, Daisy W. Leung and Vincent C. Luca.

Source: Vince Luca/X

Anna Manturova cancer Charlotte Mason Daisy W. Leung Daniel Antfolk David A. Price Elliot Medina Keiran S. M. Smalley LAG3 MHC II Nature Communications OncoDaily Oncology Qianqian Ming Srishti Singh Timothy H. Tran Vincent C. Luca

Esophageal Cancer: Symptoms, Causes, Stages, Diagnosis & Treatment

Faster, Flexible and Affordable: Mikhail Groubman on Building a Global Legacy in Clinical Research in an Untapped Market

Invest in Health Policy: A Conversation with Professor Andreas Charalambous

FDA Approves Cosibelimab-ipdl for Treatment of Metastatic or Locally Advanced Cutaneous Squamous Cell Carcinoma

Dolph Lundgren’s Fight for Life: How He Survived Kidney Cancer After 9 Years of Battle

Special Coverage