Erman Akkus: First line treatment of metastatic Colorectal Cancer in older patients

Erman Akkus, Medical Oncology Fellow at Ankara University Faculty of Medicine, shared on X:

“FOLFOX/Xelox + beva vs. 5FU/cape +beva in first line treatment of metastatic CRC in older patients.

Median age 80 and 79
•No difference in PFS, 10 vs 9.4 mo.
•No difference in OS, 19.7 vs 21.3 mo.
•grade ≥3 AEs 69% vs. 52%

~65% left sided and ~36% RAS WT.”

Oxaliplatin Added to Fluoropyrimidine/Bevacizumab as Initial Therapy for Unresectable Metastatic Colorectal Cancer in Older Patients: A Multicenter, Randomized, Open-Label Phase III Trial (JCOG1018)

Source: Erman Akkus/X

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