November, 2024
November 2024
M T W T F S S
 123
45678910
11121314151617
18192021222324
252627282930  
Preoperative Radiotherapy to Elicit Critical Immune Stimulating Effects
Aug 22, 2024, 14:07

Preoperative Radiotherapy to Elicit Critical Immune Stimulating Effects

Elisabetta Bonzano, Radiation Oncologist at San Matteo Polyclinic I.R.C.C.S. Foundation Pavia, shared a post on X about a recent paper by Simona Shaitelman et al. published in International Journal of Radiation Oncology.

“PRECISE: Preoperative Radiotherapy to Elicit Critical Immune Stimulating Effects – A Phase II Clinical Trial”

Authors: Simona Shaitelman, Huong Le-Petross, Maria Raso, Isabelle Bedrosian, Elizabeth Mitten et al.

Preoperative Radiotherapy to Elicit Critical Immune Stimulating Effects

“PRECISE: Preoperative Radiotherapy to Elicit Critical Immune Stimulating Effects – A Phase II Clinical Trial.

  • Stromal TIL increased 6-8 days following completion of boost radiotherapy (median 3.0 (IQR 1.0-6.5) prior to radiotherapy vs. median 5.0 (IQR 1.5-8.0) post-radiotherapy, p=0.0037.
  • Zero grade ≥ 3 toxicities up to 6 months following boost were experienced.
  • 94% (16/17) patients with 6-month follow-up cosmetic assessment following breast conservation had good-excellent cosmesis by physician assessment.”

Source: Elisabetta Bonzano/X