Myeloma Paper of the Day, August 16th, suggested by Robert Orlowski
Robert Orlowski shared on X:
“Myeloma Paper of the Day: Somatic mutation phasing and haplotype extension using linked-reads in myeloma helps interpret clonal evolution models at higher resolution and may be beneficial for some cases.”
Source: Robert Orlowski/X
Somatic mutation phasing and haplotype extension using linked-reads in multiple myeloma
Authors: Steven M. Foltz, Yize Li, Lijun Yao, Nadezhda V. Terekhanova, Amila Weerasinghe, Qingsong Gao, Guanlan Dong, Moses Schindler, Song Cao, Hua Sun, Reyka G. Jayasinghe, Robert S. Fulton, Catrina C. Fronick, Justin King, Daniel R. Kohnen, Mark A. Fiala, Ken Chen, John F. DiPersio, Ravi Vij and Li Ding.
Other posts featuring Robert Orlowski on OncoDaily.
Robert Orlowski, M.D., Ph.D., holds multiple positions at The University of Texas MD Anderson Cancer Center, including Chairman, Ad Interim Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics within the Division of Cancer Medicine. Additionally, he chairs the SWOG Barlogie/Salmon Myeloma Committee, which is part of the National Clinical Trials Network, dedicated to advancing new therapies and understanding the biology of myeloma.
Dr. Orlowski’s expertise lies in both clinical practice and scientific research, with a particular focus on translating laboratory discoveries into effective treatments for patients. He investigates drug resistance mechanisms in myeloma and seeks to identify predictive biomarkers for treatment response. Notably, his past contributions include leadership roles in developing proteasome inhibitors like bortezomib and carfilzomib, as well as monoclonal antibodies such as daratumumab and elotuzumab.
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