News Feed Opinion Blog Career Insight Dialogues Celebrities Oncolibrary
Positive Societies Drugs Stories History Cancer Center Near Me Cancer Types Immune Oncology Oncologist Near Me
November, 2024
November 2024
M T W T F S S
 123
45678910
11121314151617
18192021222324
252627282930  
Leveraging CRISPR to Uncover Plexin B2’s Role in Liver Metastasis
Photo from The Babak Lab/LinkedIn
Aug 14, 2024, 23:11

Leveraging CRISPR to Uncover Plexin B2’s Role in Liver Metastasis

Authors:

CRISPR

“Scientific Wednesday Leveraging CRISPR to Uncover Plexin B2’s Role in Liver Metastasis: A Path to New Cancer Therapies.

A recent study published in Nature Portfolio provides important insights into metastasis. Using a novel in vivo CRISPR activation screen, researchers identified plexin B2 as a key regulator of liver colonization in cancer. This discovery highlights the role of liver-derived signals in metastatic seeding.

Key Takeaways:

  • Plexin B2’s interaction with tumor semaphorins promotes epithelial traits essential for metastasis.
  • Blocking plexin B2 can effectively prevent liver metastases, pointing to a promising therapeutic strategy.
  • The approach offers a framework for understanding metastasis in other organs.

This research not only deepens our understanding of cancer biology but also opens new avenues for metastasis prevention. A big step forward in the fight against cancer!

Find out more in the original source.”

“This research offers valuable insights into how liver-derived factors influence cancer metastasis, with plexin B2 identified as a crucial player.

Find out more about the potential to block this pathway and how it could revolutionize how we prevent cancer spread in the latest review by The Babak Lab. ”

Source:

Ab Meijs Andreas Moor Andromachi Karakatsani Ardian Mannhart Atefeh Lafzi cancer cancer metastasis Costanza Borrelli CRISPR Davide Eletto Elena Guido Vinzoni Farah Baccouche Mhamedi Hassan Fazilaty Ilhan Acar Jonas Kretz Kristina Handler Maria Babak Marie-Didiée Hussherr Morgan Roberts Nature Nature Portfolio OncoDaily Oncology Plexin B2 Randall Platt Research Salvatore Piscuoglio Scientific Wednesday Shoichiro Kimura Srivathsan Adivarahan Tomas Valenta Xenia Ficht
Special Coverage
Blog
Nov 13, 2024, 16:51
The 11th edition of Richi Entrepreneurs has officially kicked off
Blog
Nov 13, 2024, 16:49
Dégi László Csaba: Transforming Cancer Care Together
Blog
Nov 13, 2024, 16:45
Jun Gong: The best awards are patient awards
Blog
Nov 13, 2024, 16:39
Bami Adenipekun: How being impacted by breast cancer for over 3 decades shapes the work that I do
Insight
Nov 13, 2024, 16:25
A clear picture of the ground reality
Insight
Nov 13, 2024, 16:23
Make your mark in Oncology research with JCO Oncology Advances - ASCO
Blog
Nov 13, 2024, 16:08
Evolving role of Radiation in early stage NSCLC by Dr. Annalisa Nardone
Insight
Nov 13, 2024, 16:02
Exploring New Avenues in Breast Cancer Treatment - The Babak Lab
Insight
Nov 13, 2024, 16:00
Role of antibody drug conjugates in the treatment of patients with breast cancer brain metastases
Blog
Nov 13, 2024, 15:56
Awareness campaigns have helped Increase Lung Cancer Screening Rates - IASLC
Blog
Nov 13, 2024, 15:56
Jennifer Ivanovich: Thrilled to see the announcement of the new ESMO Rare Cancers journal
Blog
Nov 13, 2024, 15:49
Toufic Kachaamy: Honored to have joined Marnee Spierer as a co-MC for Celebrate Life at City of Hope, Phoenix