Matt Wilson, Consultant Haematomogist specialising in lymphoma at The Beatson West of Scotland Cancer Centre, shared on X:
“Just published in British Journal of Haematology – an updated BSH – Haematology good practice paper on the ever-controversial topic of CNS prophylaxis in LBCL!
Pleasure to work with Kate Cwynarski, Toby Eyre, Jeff Smith, Sridhar Chaganti, Chris Fox and Pam McKay on this.
Brief summary:
- Increased emphasis on baseline screening
- ‘Offer’ HD-MTX +/or IT to patients with testicular LBCL
- ‘Consider’ HD-MTX in other high-risk patients (but omission entirely may be acceptable after risk/benefit discussion)
- Use max. 2x HD-MTX at end of systemic treatment”
Source: Matt Wilson/X
Authors: Matthew R. Wilson, Kate Cwynarski, Toby A. Eyre, Jeffery Smith, Sridhar Chaganti, Christopher P. Fox, Pamela McKay