Are high-dose steroids for immunotherapy-related toxicity harmful in the long run?

Peter Lau, Specialist Physician in Medical Oncology at Hollywood Private Hospital, shared a paper by Rik J. Verheijden et al. on X:

“Are high-dose steroids for immunotherapy-related toxicity harmful in the long run? This paper suggests they are for cancer. But was the dose of the steroid proportionate to the severity of the IO toxicity?”

Source: Peter Lau/X

Authors: Rik J. Verheijden, Jolien S. de Groot, Babs O. Fabriek, Miki N. Hew, Anne M. May, Karijn P.M. Suijkerbuijk

Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials