November, 2024
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Nelson Dusetti: One of the first publications from the Franco-Argentine Network for Pancreatic Cancer
Jul 24, 2024, 22:22

Nelson Dusetti: One of the first publications from the Franco-Argentine Network for Pancreatic Cancer

We are thrilled to announce one of the first publications from the Franco-Argentine Network for Pancreatic Cancer advancing global research on this malignancy.

This study identifies the ABCC4/MRP4 transporter as a crucial factor in pancreatic cancer aggressiveness and metastasis. ABCC4 promotes epithelial-mesenchymal transition (EMT), enhancing cell motility and chemoresistance. High ABCC4 levels correlate with EMT markers, making it a valuable prognostic marker and a potential therapeutic target, particularly for aggressive basal-like/squamous PDAC subtypes.
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The xenobiotic transporter ABCC4/MRP4 promotes epithelial mesenchymal transition in pancreatic cancer published in Frontiers

Autors: S. N. Gancedo, A. Sahores, N. Gómez, N. Di Siervi, M. May, A. Yaneff, M. G. de Sousa Serro, N. Fraunhoffer, N. Dusetti, J. Iovanna, C. Shayo, C. A. Davio, B. González

Nelson Dusetti

Source: /LinkedIn

Scientific Director of the company Predicting Med (CSO) and Chair of TRANSLATE-IT CRCM. He is also research director at INSERM. He is the Head of the Department of Translational Research and Innovative Therapies at CRCM.”