Nickolas Stabellini: Valuable insights into Health Disparities in CardioOncology and Cancer Research.

Nickolas Stabellini, MD/PhD at Case Western Reserve University, shared the following insight on X?X/Twitter:

“Just published ‘Social Determinants of Health Data Improve the Prediction of Cardiac Outcomes in Females with Breast Cancer’ in Cancers MDPI.”

Valuable insights into Health Disparities in CardioOncology and Cancer Research.

Key findings.
-The study included 4309 patients from University Hospitals.
-17.8% were NHB.
-11.3% experienced a 2-year MACE (median time-to-event = 177 days).
-Heart failure was the most prevalent MACE (6.9%).

Comparing the effect of adding individual-level SDOH data to ML models for MACE prediction:
-Improved performance across all patients (race-agnostic model).
-Enhanced performance in NHB (race-specific model).
-No improvements observed in NHW.

Impacts:
-Builds on our JNCCN publication on SDOH and Racial Disparities in breast cancer.
-Reinforces the crucial role of SDOH in health disparities.
-Highlights the need for equitable publicpolicies to address SDOH disparities.

Thanks to the awesome team of coauthors: Jennie Cullen Meyer, Justin Xavier Moore, Susan Dent, Arnethea L. Sutton, Alberto Montero, Avirup Guha.”

Source: Nickolas Stabellini/Twitter