Sonia Guedan: CAR affinity modulates CAR-T cells’ sensitivity to PD-1/PD-L1 inhibition

Sonia Guedan, shared a post on X about a recent paper titled “CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition” published in the Nature Communications.

Authors: Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B. Huppa, Sonia Guedan.                   .

“We are grateful for the reception of our latest work in Nature Communications.
There, we explore how CAR affinity modulates CAR-T cells’ sensitivity to PD-1/PD-L1-mediated inhibition.”

Proceed to the video attached to the post.
Source: Sonia Guedan/X