When only trace amounts of ctDNA are present, the MRD test you choose matters
NeXT Personal® is an ultrasensitive, tumor-informed MRD assay designed to detect disease even when ctDNA levels are very low. Because a negative result is only as informative as a test’s ability to detect the disease that’s there.
And low-level disease can still carry clinical significance.
In the landmark TRACERx study, 18% of post-surgical landmark ctDNA detections occurred below 10 parts per million (PPM). Patients with ctDNA detected at these levels had a 3-fold increased risk of recurrence compared with patients with undetectable ctDNA.¹
Cancer biology evolves.
Real-Time Variant Tracker™ is an optional supplemental result in the NeXT Personal MRD test report that tracks selected resistance and therapeutically targetable variants. This includes variants associated with NCCN guidelines-recommended and FDA-approved therapies.
Discover how comprehensive MRD monitoring with NeXT Personal can enhance your clinical practice.
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References.
- Black, JRM,. Wan JCM, et al. (2026, May 30). Clinical validity of ultrasensitive single-digit parts per million ctDNA detection in non-small cell lung cancer. ASCO Annual Meeting, Chicago, IL, United States