The 11th Mayo Clinic Symposium on Immuno-Oncology and Tumor Microenvironment Crosstalk 2026 will take place from December 11–13, 2026, at Mayo Clinic in Jacksonville, Florida, USA, with livestream participation available.

Organized by Mayo Clinic College of Medicine and Science, the symposium will bring together researchers and clinicians to discuss advances in immuno-oncology, tumor biology, and the interactions between cancer and the tumor microenvironment.

The program will explore tumor microenvironment biology, cancer immunology, immunotherapy, translational research, diagnostics, nanotechnology, and emerging therapeutic approaches. The symposium is designed to encourage interaction between basic scientists and clinical investigators while examining how discoveries in tumor biology and immune regulation can be translated into new strategies for cancer treatment.