
The IASLC 2025 Hot Topic in Basic and Translational Science: Unraveling Precancer and Early-Stage Lung Cancer meeting is a three-day event in Tokyo, Japan, dedicated to advancing the understanding and treatment of early lung cancer. Scheduled to begin on November 21, 2025, the meeting focuses on the molecular, genomic, transcriptomic, and immune mechanisms of early lung carcinogenesis. It aims to bridge the gap between basic science and clinical application by exploring emerging biomarker and diagnostic innovations (including liquid biopsies and AI) and discussing novel therapeutic pathways like targeted therapies and immunotherapy for the earliest stages of the disease.