The AACR Early Onset Cancers 2027 Conference, organized by the American Association for Cancer Research (AACR), will take place on December 5–8, 2027, at Sheraton Grand Los Angeles in Los Angeles, California, United States.

The four-day meeting will bring together cancer researchers, epidemiologists, oncologists, and translational scientists to explore the growing scientific interest in cancers diagnosed at younger ages.

The conference will provide an international platform for examining early-onset cancer biology, epidemiological patterns, and potential factors contributing to cancer development in younger populations. Topics of scientific interest include genetic susceptibility, environmental and lifestyle exposures, molecular characteristics, cancer prevention, and opportunities for earlier diagnosis and intervention.

Through scientific exchange and interdisciplinary collaboration, the meeting aims to advance understanding of early-onset malignancies and encourage research that may inform cancer prevention, screening, and treatment strategies. The conference will connect researchers working across population science, cancer biology, and clinical oncology to address important questions surrounding cancer in younger adults.