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How Aspirin can help stop cancer from spreading? – Cancer Research Institute
Mar 29, 2025, 10:45

How Aspirin can help stop cancer from spreading? – Cancer Research Institute

Cancer Research Institute shared a recent study Jie Yang and colleagues authored on LinkedIn:

“Ranging from being an affordable painkiller, to a safe blood-thinning agent for hypertensive patients, aspirin is a well known, over-the-counter option often found in medicine cabinets. Now, scientists have discovered that aspirin can also help prevent cancer metastasis.

A recent study co-authored by CRI Lloyd J. Old STAR Dr. Enrico Lugli from Humanitas Research Hospital provides details on how aspirin can help stop cancer from spreading.

The research reveals that aspirin suppresses a specific signaling molecule, Thromboxane A2, which can push T cells into an immunosuppressive state by inhibiting T cell receptor-driven kinase signaling, proliferation, and effector functions. Blocking Thromboxane A2 with aspirin enhanced T cell immunity against cancer metastasis.

Continue to discover how these findings could open new possibilities for the use of aspirin in preventing cancer spread.”

Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity

Authors: Jie Yang et al.

aspirin

Further Reading:

Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity

55% Reduction in Cancer Recurrence? Aspirin Shows Promise – CancerWorld

Aspirin after completion of standard adjuvant therapy for colorectal cancer (ASCOLT)