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New research from Dr. Jung-Min Lee has identified a potential drug to treat ovarian cancers – NCI Center for Cancer Research
Apr 17, 2024, 19:06

New research from Dr. Jung-Min Lee has identified a potential drug to treat ovarian cancers – NCI Center for Cancer Research

NCI Center for Cancer Research shared on LinkedIn:

“Milestones Monday: Ovarian cancer is the most lethal of all gynecological cancers.

Nearly a decade ago, the outlook for people diagnosed with ovarian cancer improved when drugs called PARP inhibitors were approved as a treatment for the disease. However, a new challenge has emerged for doctors who treat ovarian cancer: how to treat patients whose cancer has become resistant to PARP inhibitors, as most eventually do.

New research from Dr. Jung-Min Lee has identified a potential drug to treat ovarian cancers that have developed resistance to PARP inhibitors and a possible biomarker for those most likely to benefit from it.”

High-grade serous carcinoma ovarian cancer cells with hematoxylin and eosin (H&E) staining. Ovarian cancer is often diagnosed when it is already advanced, and treatment options are often limited. CCR researchers have now identified a drug that could be beneficial for a subset of patients whose cancer has grown after treatment with PARP inhibitors. They have also identified the gene activity that may indicate which patients are good candidates for the new drug. A clinical trial to evaluate its effects is underway. Credit: Maria Del Carmen Rodriguez Pena, M.D., CCR, NCI, NIH; Markku M. Miettinen, M.D., Ph.D., CCR, NCI, NIH; SPGM, FNL, NCI, NIH

Source: NCI Center for Cancer Research/LinkedIn


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