Roger Spencer is the Chief Executive of The Christie NHS Foundation Trust, Europe’s largest single-site cancer centre, a position he has held since December 2013. Under his leadership, The Christie became the first specialist NHS trust in the UK to be rated Outstanding twice by the Care Quality Commission.
Spencer oversaw the delivery of the UK’s first NHS high-energy proton beam therapy service and the development of the Paterson cancer research facility, strengthening the integration of world-class research with patient care. He has expanded the Trust’s regional network of radiotherapy and chemotherapy centres across Greater Manchester and Cheshire, serving a population of over 3 million.
As Chair of the Greater Manchester Cancer Alliance, Spencer plays a key role in regional cancer system leadership. He also guides The Christie’s long-term innovation strategy, Future Christie, focusing on modernising patient care and integrating research with clinical services.
The 100 CEOs featured here reflect the diversity and complexity of modern oncology leadership. In 2025, some lead the world’s largest cancer institutions; others guide specialized societies or emerging innovators. What unites them is responsibility: for millions of patients, for the integrity of science, and for the future direction of cancer care globally.
This list is not a celebration of power, but a recognition of stewardship, accountability, and impact – and of the leaders whose choices continue to shape the fight against cancer. For the many deserving individuals not mentioned in this list, we will continue to acknowledge, honor and elevate your voices in our daily publications from across the world.
See the full list of The 100 Most Influential CEOs in Oncology in 2025, and stay tuned for other special category nominations.
