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Toby Eyre: R-Ibrutinib vs R-chemo as first line for Metastatic Cell Lymphoma
Nov 8, 2024, 15:14

Toby Eyre: R-Ibrutinib vs R-chemo as first line for Metastatic Cell Lymphoma

Toby Eyre, Specialist in Lymphoma CLL and Senior lecturer in University of Oxford, shared the post on X:

ENRICH Primary analysis.

-4y follow up

-R-Ibrutinib vs R-chemo (BR or RCHOP) 1L MCL

-IR superior PFS to ICT HR 0.69 p=0.003

-Low haem toxicity

-Earlier increased QoL with R-Ibr

-Major benefit seen vs RCHOP subgroup

-1st 1L RCT across any lymphoma (not included CLL) showing non-chemo superior to ICT.”

 

Toby Eyre: R-Ibrutinib vs R-chemo as first line for Metastatic Cell Lymphoma