Thor Halfdanarson/mayoclinic.org
May 20, 2025, 14:45
Thor Halfdanarson: Lot to unpack from the excellent NORDIC NEC 2 Study
Thor Halfdanarson, Medical Oncologist at the Mayo Clinic, shared a post on X about recent article Halfdan Sorbye and colleagues authored:
“Lot to unpack from the excellent NORDIC NEC2.
– ORR: 31% for NEC (mostly plat/eto) – this is NOT SCLC
– ORR: 27% for G3 NETs (mostly TMZ-based)
– Immediate progression: 41% of NECs, 21% G3 NETs
– PFS: 3.4 m NEC; 7.4 G3 NETNECs are really bad cancers!”
Title: Characteristics and treatment outcome in a prospective cohort of 639 advanced high-grade digestive neuroendocrine neoplasms (NET G3 and NEC). The NORDIC NEC 2 study
Authors: Halfdan Sorbye, Geir Olav Hjortland, Lene Weber Vestermark, Morten Ladekarl, Johanna Svensson, Anna Sundlöv, Eva Tiensuu Janson, Herish Garresori, Eva Hofsli, Christian Kersten, Hege Elvebakken, Per Pfeiffer, Siren Morken, Jorg Assmus, Inger Marie Bowitz Lothe, Elizaveta Tabaksblat, Ulrich Knigge, Anne Couvelard, Aurel Perren, Seppo W. Langer
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