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Thor Halfdanarson: Is sarcoma a potential manifestation of MEN1?

Thor Halfdanarson/mayoclinic.org

Dec 1, 2024, 10:09

Thor Halfdanarson: Is sarcoma a potential manifestation of MEN1?

Thor Halfdanarson, Vice President at the North American Neuroendocrine Tumor Society, shared on X about recent paper by him as co-author, titled “Sarcomas arising in MEN1 patients: demonstrating LOH of the MEN1 locus and loss of menin expression” published on Springer Nature.

Authors: Rachel S. van Leeuwaarde, Thorvardur R. Halfdanarson, Shwetha M. Sudhakar, Ruud W. J. Meijers, Andrew L. Folpe, Lodewijk A. A. Brosens.

“Is sarcoma a potential manifestation of MEN1…? In this small case series, 5 patients with a MEN1 and a sarcoma are described and all had sarcomas loss of heterozygosity of the MEN1 gene and loss of expression of menin. Study based on clinic observation.”

Andrew L. Folpe cancer Lodewijk A. A. Brosens MEN1 OncoDaily Oncology Rachel S. van Leeuwaarde Ruud W. J. Meijers sarcoma Shwetha M. Sudhakar Springer Nature Thor Halfdanarson

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