Sendurai Mani: Accumulation of CD38 in Hybrid Epithelial/Mesenchymal Cells Promotes Immune Remodeling and Metastasis in Breast Cancer
Sendurai Mani, Professor of Medicine at Brown University, shared NCI Division of Cancer Biology‘s post on LinkedIn, adding:
“Thanks to the NCI Division of Cancer Biology for the amazing support, which makes all the difference in understanding how cancer develops and developing novel ways to treat cancer.”
Quoting NCI Division of Cancer Biology’s post:
“In a study supported by our division, Tanvi Visal, George Calin, Sendurai Mani, et al. showed that hybrid cells with epithelial and mesenchymal traits express increased levels of CD38 to promote immunosuppression and metastasis in triple-negative breast cancer.
They also found that targeting CD38 enhances anti-tumor immunity and immunotherapy in preclinical breast tumor models.”
Authors: Tanvi Visal, George Calin, Sendurai Mani, et al.
More posts featuring NCI Division of Cancer Biology.
-
Challenging the Status Quo in Colorectal Cancer 2024
December 6-8, 2024
-
ESMO 2024 Congress
September 13-17, 2024
-
ASCO Annual Meeting
May 30 - June 4, 2024
-
Yvonne Award 2024
May 31, 2024
-
OncoThon 2024, Online
Feb. 15, 2024
-
Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023