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Rashid K. Sayyid: COSMIC-313 final results
Rashid K. Sayyid/X
Feb 19, 2025, 17:22

Rashid K. Sayyid: COSMIC-313 final results

Rashid K. Sayyid, Urology Resident in the Department of Surgery at Augusta University, shared a post on X:

“COSMIC-313: Final results.

Ipi + Nivo +/- Cabo in aRCC pts (n=885, f/u: 45 mo):

  • PFS benefit: 16.6 vs 11.2 mo (limited to IMDC int risk only: 22.1 vs 11.3 mo; poor risk: 9.5 vs 11.2 mo).
  • No OS benefit in overall, int or poor risk groups.
  • Triplet combo not well tolerated (only 50% tolerated all 4 cycles of Ipi).
  • RNA seq data Tumors w/ M2-like macrophages benefited most from cabo addition to ipi + nivo.”

Rashid K. Sayyid: COSMIC-313 final results

Augusta University cancer COSMIC-313 fight against cancer Global fight against cancer IMDC OncoDaily Oncology Rashid K. Sayyid Urology
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