Raffaele Colombo/LinkedIn
Apr 12, 2025, 02:19
Raffaele Colombo: Sacituzumab Govitecan (SG) vs Sacituzumab Tirumotecan (Sac-TMT)
Raffaele Colombo, Associate Director of Medicinal Chemistry at Zymeworks, shared a post on X:
“Sacituzumab govitecan (SG) vs sacituzumab tirumotecan (Sac-TMT)
= antibody
≈ DAR (7.6 vs 7.4)
≠ conjugation chemistry (maleimide vs pyrimidine)
≈ linker (except conjugation part)
= carbonate cleavable group
≠ payload structure and properties (SN-38 vs KL610023).”
-
Challenging the Status Quo in Colorectal Cancer 2024
December 6-8, 2024
-
ESMO 2024 Congress
September 13-17, 2024
-
ASCO Annual Meeting
May 30 - June 4, 2024
-
Yvonne Award 2024
May 31, 2024
-
OncoThon 2024, Online
Feb. 15, 2024
-
Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023
May 9, 2025, 10:29
May 9, 2025, 10:15
May 9, 2025, 09:39
May 9, 2025, 09:37
May 9, 2025, 09:22
May 9, 2025, 09:15
May 9, 2025, 08:15