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Assessment of Predisposition Genes in High-Grade Serous Ovarian Carcinoma via Germline and Tumour Sequencing

Ovarian Cancer

Feb 5, 2025, 07:02

Assessment of Predisposition Genes in High-Grade Serous Ovarian Carcinoma via Germline and Tumour Sequencing

Elvina Almuradova, Medical Oncologist Ambassador at European School of Oncology, shared on X:

“New study identifies key genes in ovarian cancer risk

PALB2 and ATM confirmed as predisposition genes

LLGL2 emerges as a novel candidate Other proposed genes fail validation

Integrating tumor sequencing is crucial!!”

Assessment of candidate high-grade serous ovarian carcinoma predisposition genes through integrated germline and tumour sequencing | npj Genomic Medicine

Authors: Deepak N. Subramanian, Maia Zethoven, Kathleen I. Pishas, Evanny R. Marinović, Simone McInerny, Simone M. Rowley, Prue E. Allan, Lisa Devereux, Dane Cheasley, Paul A. James and Ian G. Campbell

Assessment of Predisposition Genes in High-Grade Serous Ovarian Carcinoma via Germline and Tumour Sequencing

cancer Dane Cheasley Deepak N. Subramanian Elvina Almuradova Evanny R. Marinović Ian G. Campbell Kathleen I. Pishas Lisa Devereux Maia Zethoven OncoDaily Oncology Paul A. James Prue E. Allan Simone M. Rowley Simone McInerny

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