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Erythropoietin Promotes an Immunosuppressive Tumor Microenvironment in Liver Cancer Models – NCI Division of Cancer Biology
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Jul 9, 2025, 19:55

Erythropoietin Promotes an Immunosuppressive Tumor Microenvironment in Liver Cancer Models – NCI Division of Cancer Biology

NCI Division of Cancer Biology shared on LinkedIn:

“An NIH-funded study showed that erythropoietin (a hormone that stimulates the production of red blood cells) secreted by tumor cells promotes an immunosuppressive tumor microenvironment in liver cancer models. It also found that blocking erythropoietin signaling enhances immune responses to tumors.”

NCI Division of Cancer Biology

Title: Tumor-derived erythropoietin acts as an immunosuppressive switch in cancer immunity

Authors: David Kung-Chun Chiu, Xiangyue Zhang, Bowie Yik-Ling Cheng, Qiang Liu, Kazukuni Hayashi, Bo Yu, Ryan Lee, Catherine Zhang, Xiuli An, Jayakumar Rajadas, Nathan E. Reticker-Flynn, Erinn B. Rankin, Edgar G. Engleman

Read full article.

NCI Division of Cancer Biology

Read an insightful article about Liver Cancer.

NCI Division of Cancer Biology

Bo Yu Bowie Yik-Ling Cheng Catherine Zhang David Kung-Chun Chiu Edgar G. Engleman Erinn B. Rankin Jayakumar Rajadas Kazukuni Hayashi liver cancer Nathan E. Reticker-Flynn NCI Division of Cancer Biology Qiang Liu Ryan Lee Xiangyue Zhang Xiuli An
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