December, 2024
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Liana Hayrapetyan: The impact of radiation therapy in combination with DNA-PKcs Inhibition in head and neck cancer
Dec 4, 2024, 15:37

Liana Hayrapetyan: The impact of radiation therapy in combination with DNA-PKcs Inhibition in head and neck cancer

Liana Hayrapetyan, MD-PhD at University of Bern, shared on LinkedIn:

“I’m excited to share one of the projects I worked on during my PhD at the Universität Bern! The paper is now published in Molecular Cancer Therapeutics!

In this study, we investigated the impact of radiation therapy in combination with DNA damage repair pathway inhibition in head and neck cancer models. Our findings reveal that HPV status and p53 protein expression are critical in determining treatment outcomes in our experimental models. These factors may help shape the potential benefits of this treatment strategy in specific patient populations.

For more details, check out the paper. A big thanks to all my coauthors, collaborators, and supervisors!”

HPV and p53 Status as Precision Determinants of Head and Neck Cancer Response to DNA-PKcs Inhibition in Combination with Irradiation 

Authors: Liana Hayrapetyan, Selina M. Roth, Aurélie Quintin, Lusine Hovhannisyan, Matúš Medo, Rahel Riedo, Julien G. Ott, Joachim Albers, Daniel M. Aebersold, Yitzhak Zimmer, Michaela Medová

Liana Hayrapetyan