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Katy Beckermann: Secondary Analysis of the TITAN Trial
Apr 1, 2025, 04:49

Katy Beckermann: Secondary Analysis of the TITAN Trial

Katy Beckermann, Medical Director of GU Clinical Research at Tennessee Oncology, posted on X:

“New analysis from the TITAN trial:

In mCSPC patients treated with apalutamide:

  • Discordant progression occurred in 52.2% of patients (60 of 115) in the apalutamide group and 27.5% (58 of 211) in the placebo group (p < 0.001).

Takeaway: PSA alone isn’t enough—routine imaging is critical!”

“Radiographic Progression Without Corresponding Prostate-specific Antigen Progression in Patients with Metastatic Castration-sensitive Prostate Cancer Receiving Apalutamide: Secondary Analysis of the TITAN Trial.”

Authors: Wataru Fukuokaya, Takafumi Yanagisawa, Keiichiro Mori, Fumihiko Urabe, Pawel Rajwa, Alberto Briganti, Shahrokh F. Shariat, Takahiro Kimura

Katy Beckermann