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Discover the latest advancements in treating HER2-negative breast cancer brain metastases – Media Medic
Jun 15, 2024, 04:45

Discover the latest advancements in treating HER2-negative breast cancer brain metastases – Media Medic

Media Medic shared a post on LinkedIn:

ASCO China Voice | Professor Min Yan: Utidelone Combined with Bevacizumab is Safe and Effective for Treating Brain Metastases in HER2-Negative Breast Cancer.

Brain metastasis from breast cancer has a high incidence, second only to lung cancer. Previous studies have shown that patients with brain metastases have poorer survival compared to those without brain metastases, with HER2-negative breast cancer brain metastasis patients having an even worse prognosis. Due to the blood-brain barrier (BBB), many drug treatments have limited intracranial objective response rates (ORR). Utidelone, a novel microtubule inhibitor developed in China, has shown potential for treating brain metastases due to its unique physicochemical properties that allow it to penetrate the BBB. At the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, a multicenter phase II study led by Professor Min Yan from Henan Cancer Hospital was selected for presentation. This study explored the efficacy and safety of utidelone combined with bevacizumab in treating HER2-negative breast cancer brain metastases. Oncology Frontier invited Professor Min Yan to discuss the progress in treating breast cancer brain metastases, the study design and findings, and future perspectives.

Discover the latest advancements in treating HER2-negative breast cancer brain metastases!”

Source: Media Medic/LinkedIn