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Estela Rodriguez: Dr Richard Kim on Translating Recent ASCO Colorectal Abstracts into Practice
Aug 2, 2025, 14:31

Estela Rodriguez: Dr Richard Kim on Translating Recent ASCO Colorectal Abstracts into Practice

Estela Rodriguez, Associate Director of Community Outreach- Thoracic Oncology at Sylvester Comprehensive Cancer Center, shared a post on X:

“Great talk by Dr Richard Kim on translating recent ASCO Colorectal abstracts into Practice regarding IO therapy, ctDNA monitoring and treatment escalation.

Translating Evidence to Daily Practice

  • Reflex-test up front: Ensure every new stage II-III colon tumor gets MMR/MSI testing at diagnosis so eligible patients aren’t missed.
  • Make the combo the default: For every resected stage III dMMR colon cancer patient who can tolerate oxaliplatin, I will recommend mFOLFOX6 (6 mo) plus atezolizumab continued to 12 mo, given the ≥10-point jump in 3-year DFS (86.4 % vs 76.6 %; HR 0.50)
  • Flag the knowledge gaps: We still don’t know if chemotherapy is truly needed or how short we can make the IO course-raise this in every consent talk.
  • Stage II MSI-high: Continue case-by-case decisions (observation vs brief chemo) or clinical-trial referral; ATOMIC doesn’t yet justify atezolizumab in this setting.”

Estela Rodriguez

More posts featuring Estela Rodriguez.