Emre Yekedüz: Fantastic Review For Non-clear Cell Renal Cell Carcinoma
Emre Yekedüz, Associate Professor of Medical Oncology at Ankara University, shared a post on X:
“A fantastic review for non-clear cell renal cell carcinoma in Nature Reviews Urology
Time to tailor, not generalize:
Genotype-driven subtyping (e.g. MET, FH, TSC-mTOR, ALK, MITF, SMARCB1) enables precision therapy.
Cabozantinib and savolitinib show promise in MET-driven tumors.
TSC-mTOR alterations in oncocytic/chromophobe RCCs pose unique challenges, sparking new trials.
TME varies by subtype, shaping immunotherapy use.”
Title: Molecular and therapeutic landscape of non-clear cell renal carcinoma
Authors: Prerna R. Nepali, Ahmed Eraky, Kennedy E. Okhawere, Navneet Dogra, Reza Mehrazin, Ketan Badani, Natasha Kyprianou
You can read the Full Article on Nature Reviews Urology
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