Elvina Almuradova/X
Jun 29, 2025, 10:35
Elvina Almuradova: Could Breast Cancer Treatments Impact Alzheimer’s risk?
Elvina Almuradova, Associate Professor of Oncology at the European Institute of Oncology, shared a post on LinkedIn:
“Could breast cancer treatments impact Alzheimer’s risk?
A large Korean cohort study of 70,701 breast cancer survivors found that they had an 8% lower risk of developing Alzheimer’s disease compared with age-matched cancer-free women (SHR: 0.92).
Key findings:
• The reduced risk was more pronounced in women aged ≥65.
• Radiation therapy was significantly associated with lower AD risk (HR: 0.77).
• This protective association diminished after 5 years of survivorship.
• No significant association was found with anthracycline, taxane, trastuzumab, or endocrine therapies.While cognitive impairment (“chemobrain”) remains a concern, this study suggests that standard breast cancer treatments may not increase – and may even lower – long-term AD risk.”
Title: Alzheimer Disease in Breast Cancer Survivors
Authors: Su-Min Jeong, Wonyoung Jung, Hyeonjin Cho, Hea Lim Choi, Keun Hye Jeon, Ki-Woong Nam, Yun-Gyoo Lee, Bongseong Kim, Kyungdo Han, Dong Wook Shin
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